American adults have larger waists than their British counterparts, which can account for their significantly greater prevalence of type 2 diabetes, a study suggested. The sole factor that helped explain the diabetes differential was waist circumference, according to the researchers.
Key point - fat cells deposited in the viscera are distinct from those found elsewhere.
"Central fat cells have a higher turnover rate of triglycerides and produce more proinflammatory and metabolic markers," the researchers explained.
In addition, these cells draw free fatty acids to the liver, which can further contribute to insulin resistance and ultimately, to diabetes, according to the researchers.